CB-13 (CRA13, SAB-378) is a cannabinoid drug, which acts as a potent agonist at both the CB<sub>1</sub> and CB<sub>2</sub> receptors, but has poor bloodâÂÂbrain barrier penetration, and so produces only peripheral effects at low doses, with symptoms of central effects such as catalepsy only appearing at much higher dose ranges. It has antihyperalgesic properties in animal studies, and has progressed to preliminary human trials.
As of October 2015 CB-13 is a controlled substance in China.
CB-13 is a Schedule I controlled substance in North Dakota.