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CABLES1

CDK5 and ABL1 enzyme substrate 1 is a protein that in humans is encoded by the CABLES1 gene.

CABLES1 is a cyclin-dependent kinase (CDK)-binding protein that plays a role in proliferation and/or cell differentiation. [supplied by OMIM]. It is a tumor suppressor gene which losing it (by mutations, knockout, knockdown or inactivation) may lead to colorectal cancer CRC.

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