Buzuluksky District () is an administrative and municipal district (raion), one of the thirty-five in Orenburg Oblast, Russia. It is located in the west of the oblast. The area of the district is . Its administrative center is the town of Buzuluk (which is not administratively a part of the district). Population: 31,071 (2010 Census);
Within the framework of administrative divisions, Buzuluksky District is one of the thirty-five in the oblast. The town of Buzuluk serves as its administrative center, despite being incorporated separately as an administrative unit with the status equal to that of the districts.
As a municipal division, the district is incorporated as Buzuluksky Municipal District. The Town of Buzuluk is incorporated separately from the district as Buzuluk Urban Okrug.
In the Lower Triassic of Buzuluksky District fossils of temnospondyls and primitive reptiliomorphs were found. Extinct taxa of the Induan stage are Selenocara, Tupilakosaurus, Syrtosuchus and Axitectum. Younger animals from the Lower Olenekian are Benthosuchus, Wetlugasaurus, Trematotegmen, Thoosuchus, Qantas, Angusaurus, Dromotectum, Selenocara, Prothoosuchus and probably Tupilakosaurus.