Brush Creek is a stream in Platte County in the U.S. state of Missouri. It is a tributary of the Missouri River.
Brush Creek was so named on account of brush near its course.
Brush Creek headwaters northwest of Tiffany Springs, Kansas City beside Interstate 29 and flows west-southwest for about 4 miles. Then, around Interstate 435 the stream turns southward and travels about 5 miles before reaching the Missouri River.
There are 2 named direct tributaries of Brush Creek, Hayes Creek and Naylor Creek.