Bristol is an unincorporated community in Prowers County, Colorado, United States.
Bristol was established in 1906. The community was named after C. H. Bristol, a railroad official. The Bristol, Colorado, post office operated from July 1, 1908, until November 2, 1997. The U.S. post office at Holly, Colorado, (ZIP Code 81047) now serves Bristol postal addresses.
Bristol is located on U.S. highway route 385 in Prowers County at coordinates at an elevation of .