Briona is a comune (municipality) in the Province of Novara in the Italian region Piedmont, located about northeast of Turin and about northwest of Novara. As of 31 December 2004, it had a population of 1,196 and an area of .
The municipality of Briona contains the frazioni (subdivisions, mainly villages and hamlets) San Bernardino and Proh, where is located a Renaissance castle.
Briona borders the following municipalities: Barengo, Caltignaga, Carpignano Sesia, Casaleggio Novara, Castellazzo Novarese, Fara Novarese, Momo, San Pietro Mosezzo, and Sillavengo.