Brignole is a surname. Notable people with the surname include:
- Angelo Brignole (1924âÂÂ2006), Italian racing cyclist
- Dario Brignole (born 1968), sports and broadcasting agent based in the United States of America
- Giacomo Luigi Brignole (1797âÂÂ1853), Catholic Cardinal and Camerlengo of the Sacred College of Cardinals
- Giacomo Maria Brignole (1724âÂÂ1801), the 176th and 184th Doge of the Republic of Genoa
- Giuseppe Brignole (1703âÂÂ1769), Genoese nobleman and father of Maria Caterina Brignole, Princess of Monaco
- Maria Caterina Brignole (1737âÂÂ1813), Princess consort of Monaco by marriage to Honoré III, Prince of Monaco
- Maria Brignole Sale De Ferrari, Duchess of Galliera (1811âÂÂ1888), Italian noblewoman and philanthropist
- Anna Pieri Brignole Sale (1765âÂÂ1815), Sienese noble and court official
See also