Brenessa Thompson (born 22 July 1996) is a Guyanese sprinter who specializes in 100m and 200m.
She represented Guyana in the 2014 World Junior Championships in Eugene, Oregon, where she made the semi-finals in the 100m. She has a personal best in the 100m of 11.14 and holds the Guyanese record in the 200m with a time of 23.19.