Brazil competed at the 2020 Summer Paralympics in Tokyo, Japan from 24 August to 5 September 2021.
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Brazil collected one quota place at the 2019 Para Archery World Championships held in Den Bosch, Netherlands. In March 2021, Brazil gained four more quotas at the Americas Continental Qualification Tournament, held in Monterrey, Mexico.
|- |align=left|Hélcio Perilo |align=left|Men's individual W1 |622 |10 | |<br> W 132âÂÂ129 |<br> L 129âÂÂ140 |colspan=3|did not advance |- |align=left|Andrey de Castro |align=left|Men's individual compound |669 |29 | <br> L 135âÂÂ142 |colspan=5|did not advance |- |align=left|Heriberto Rocca |align=left|Men's individual recurve |581 |27 |<br> L 4âÂÂ6 |colspan=5|did not advance
|- |align=left|Rejane Silva |align=left|Women's individual W1 |525 |11 | |<br>L 107âÂÂ115 |colspan=4|did not advance |- |align=left|Jane Karla Gogel |align=left|Women's individual compound |688 |4 | colspan=2 | <br>L 140âÂÂ146 |colspan=4|did not advance |- |align=left|FabÃÂola Dergovics |align=left|Women's individual recurve |572 |11 |<br>W 6âÂÂ4 |<br>W 7âÂÂ1 |<br>L 1âÂÂ7 |colspan=3|did not advance
|- |align=left|Hélcio Perilo<br>Rejane Silva |align=left|Mixed team W1 |1147 |7 |colspan=2 | <br> L 126âÂÂ131 |colspan=3|did not advance |- |align=left|Andrey de Castro<br>Jane Karla Gogel |align=left|Team compound open |1357 |9 | | <br> L 142âÂÂ145 |colspan=4|did not advance |- |align=left|Heriberto Roca<br>FabÃÂola Dergovics |align=left|Team recurve open |1153 |11 | | <br> L 1âÂÂ5 |colspan=4|did not advance
Lucas Prado, Fábio Bordignon, Petrúcio Ferreira dos Santos, Yohansson Nascimento, Mateus Evangelista, Marivana Oliveira and Izabela Campos are among the athletes to represent Brazil at the 2020 Summer Paralympics.
Brazil competed in cycling at the 2020 Summer Paralympics.
Brazil have qualified after defeating Argentina in the final of the 2018 IBSA World Blind Football Championship.
Brazil have qualified one male and one female teams to the Paralympics after being in the top three in the 2018 IBSA World Goalball Championships in Malmö, Sweden.
<small>Qualification Legend: FA = Qualify to medal final; SF = Qualify to semifinal</small>
Brazil qualified four boats for all rowing classes into the Paralympic regatta. Two crews (men's single and mixed double sculls) qualified after successfully entering the top seven for men's single sculls and top eight for mixed double sculls at the 2019 World Rowing Championships in Ottensheim, Austria. Meanwhile, two more crews, qualified after women's single sculls win the 2021 Final Paralympic Qualification Regatta, in Gavirate, Italy, and mixed coxed four after winning the silver medal.
<small>Qualification Legend: FA=Final A (medal); FB=Final B (non-medal); R=Repechage</small>
Brazil entered one athletes into the Paralympic competition. Alexandre Galgani successfully break the Paralympic qualification at the 2019 WSPS World Cup which was held in Al Ain, United Arab Emirates.
36 Brazilian swimmers will compete in swimming at the 2020 Summer Paralympics
Brazil entered ten athletes into the table tennis competition at the games. Eight qualified from 2019 Parapan American Games which was held in Lima, Peru and two others via World Ranking allocation.
Brazil qualified three athletes to compete at the Paralympics competition. Two of them confirmed to compete at the games by winning the gold medal at the 2021 Americas Qualification Tournament in San Jose, Costa Rica, while the other athlete qualified by placing second at the world ranking.
The women's sitting volleyball team qualified for the 2020 Summer Paralympics after being finalist at the 2019 Parapan American Games, since the United States were already qualified after being World Champions.
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Brazil qualified seven players entries for wheelchair tennis. Five of them qualified by the world rankings, while the other qualified by received the bipartite commission invitation allocation quotas.