Brachyhesma isae, or Brachyhesma (Brachyhesma) isae, is a species of bee in the family Colletidae and the subfamily Euryglossinae. It is endemic to Australia. It was described in 1977 by Australian entomologist Elizabeth Exley.
The species occurs in north-west Queensland. The Type locality is 6 km east of Mount Isa.
The adults are flying mellivores. Flowering plants visited by the bees include Eucalyptus and Tristania species.