Bolshoye Yefimovo () is a rural locality (a village) in Nizhne-Vazhskoye Rural Settlement, Verkhovazhsky District, Vologda Oblast, Russia. The population was 104 as of 2002.
Bolshoye Yefimovo is located 7 km southwest of Verkhovazhye (the district's administrative centre) by road. Pyatino is the nearest rural locality.