Bolshoye Lubozino () is a rural locality (a village) in Kichmengskoye Rural Settlement, Kichmengsko-Gorodetsky District, Vologda Oblast, Russia. The population was 55 as of 2002.
Bolshoye Lubozino is located 31 km southwest of Kichmengsky Gorodok (the district's administrative centre) by road. Mikheyevo is the nearest rural locality.