Bolshoye Chertishchevo () is a rural locality (a village) in Sosnovskoye Rural Settlement, Vologodsky District, Vologda Oblast, Russia. The population was 1 as of 2002.
Bolshoye Chertishchevo is located 27 km southwest of Vologda (the district's administrative centre) by road. Maloye Chertishchevo is the nearest rural locality.