Boca do Acre (Mouth of Acre) is a municipality located in the Brazilian state of Amazonas. Its population was 34,635 (2020) and its area is 22,349 km<sup>2</sup>.
The municipality holds 92% of the Mapiá-Inauini National Forest, created in 1989. It also contains the Arapixi Extractive Reserve, created in 2006.