Bit-Amukani (in the Aramaic Assur Ostracon þwkn; Assyrian <sup>m</sup>A-muk-ka-nu; Babylonian <sup>di</sup>Bit U-ka-a-ni, <sup>di</sup>U-ka-nu; lit. House of Amukani) was a tribe, proto-state founded by Chaldeans in southern Mesopotamia which stretched from southeast of Nippur to the area of Uruk. It is considered to have been one of the most powerful Chaldean tribes, next to Bët-Iakin and Bët-Dakkà «ri.
As early as 732 BCE, it was ruled by prince Ukinzer (also known as Mukin-zeri or Nabu-mukin-zeri) who became a king of Babylon in 732 BCE instead of Nabu-shum-ukin II whom he superseded. Later, Tiglath-pileser III devastated Bit-Amukani for the second time and defeated Mukin-zeri. Shalmaneser III (856-824) inscriptions note that two Chaldean leaders (Muà ¡allim-Marduk of Bët-AmukÃÂni and Adënu of Bët-Dakkà «ri) carried silver, gold, tin, bronze, elephant tusks, elephant skins, ebony and sissoowood (or meskannu wood) as a tribute to the King of Assyria.
Though unconfirmed, the economy of Bët-Amà «kÃÂni probably relied on producing dates.
Tiglath-pileser III described his genocide of Bit-Amukani with the words: "the land Bit-Amukani I threshed as with a threshing instrument. I took all of its people (and) its property to Assyria." Although Tiglath-pileser III's writings testify about conflict with Bët-Amà «kÃÂni, Bët-Amà «kÃÂni never went extinct but actually remained important through later Babylonian history.
Sennacherib's inscriptions note that Bit-Amukani consisted of 39 walled cities and 350 villages. Its capital was Sapia (Assyrian Sapëya or à  apëya).