William Nelson may refer to:
- William Nelson (British judge) (born c. 1981), British district judge
- William Nelson (MP) (c. 1462âÂÂ1525), member of parliament for the City of York
- William Nelson (New York politician) (1784âÂÂ1869), U.S. congressman for New York
- William Nelson (Wisconsin politician) (1839âÂÂ1913), member of the Wisconsin State Senate
- William Nelson (wrestler), American wrestler who won a bronze medal at the 1904 Olympics
- William Nelson, 1st Earl Nelson (1757âÂÂ1835), elder brother of Horatio Nelson, 1st Viscount Nelson
- William "Bull" Nelson (1824âÂÂ1862), Union army general in the American Civil War
- William E. Nelson (died 1991), murdered by his wife Omaima Nelson
- William G. Nelson (fl. 1980sâÂÂ2020s), American cancer researcher and professor
- Harold Nelson (athlete) (William Harold Nelson, 1923âÂÂ2011), New Zealand runner
- William L. Nelson (politician) (1875âÂÂ1946), U.S. congressman for Missouri
- William L. Nelson (Medal of Honor) (1918âÂÂ1943), World War II Medal of Honor recipient
- William Lambie Nelson (1807âÂÂ1887), member of the Queensland Legislative Assembly
- William T. Nelson (1908âÂÂ1994), U.S. Navy rear admiral
- William Rockhill Nelson (1841âÂÂ1915), American journalist and publisher
- William Nelson (industrialist) (1843âÂÂ1932), New Zealand farmer and industrialist
- William Nelson (inventor) (died 1903), American inventor killed by own invention
- William Nelson Jr. (1754-1813), Virginia politician, professor, lawyer and judge, son of William Nelson (governor)
See also