Big Sandy Creek is a long third-order tributary to the Niobrara River in Holt County, Nebraska.
Big Sandy Creek rises on the Elkhorn River divide about southeast of School No. 188 in Holt County and then flows north and northeast to join the Niobrara River about northwest of Badger School.
Big Sandy Creek drains of area, receives about of precipitation, and is about 1.29% forested.