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Best Medicine

Best Medicine is an American medical comedy drama television series based on the British television series Doc Martin created by Dominic Minghella. The show premiered on Fox on January4, 2026. In March 2026, Fox renewed the series for a second season.

Premise

Brilliant but brusque Dr. Martin Best moves from a prestigious hospital position in Boston to a private practice in the small fishing village of Port Wenn, Maine where he vacationed as a child. As he solves mysteries behind unusual health conditions affecting the townsfolk, he struggles to integrate with them as well as a pathological blood phobia resulting from an operation on a young girl that reminded him of losing his older sister Rosemary as a child, while reconnecting with his aunt, a local lobster woman.

Cast

Main

  • Josh Charles as Martin Best, MD, a successful and brilliant Harvard Medical School-educated heart surgeon with a lack of bedside manner and a severe blood phobia. He is straightforward with patients, delivering diagnoses and advice without protecting their feelings, though he is no less concerned about their health. He had an older sister named Rosemary who died in a car crash when they were children, inspiring him to pursue medicine, and developed his phobia when operating on a young girl who reminded him of Rosemary.
  • Abigail Spencer as Louisa Gavin, a schoolteacher
  • Josh Segarra as Mark Mylow, the town's sheriff and Louisa's ex-fiancé
  • Cree as Elaine Denton, Dr.Best's administrative assistant who wants to become a YouTube influencer
  • Annie Potts as Aunt Sarah, Dr.Best's aunt and the local lobster woman

Recurring

  • Stephen Spinella as Greg Garrison, the proprietor of The Salty Breeze, the village's seafood restaurant, who refers to himself and his significant other, with whom he owns a pet pig named Brisket, as the "Dynamic Duo"
  • Jason Veasey as George Brady, Greg's significant other and the executive chef of The Salty Breeze
  • Carter Shimp as Al Large, Bert's son and coworker who becomes interested in Elaine
  • John DiMaggio as Bert Large, a local contractor
  • Clea Lewis as Sally Mylow, the town's pharmacist and Mark's mother
  • Michael Potts as Gilbert Carlisle, Dr. Best's first patient upon arrival in town
  • Didi Conn as Geneva Potter, a senior Port Wenn resident
  • Ben Lewis Doherty as Peter Cronk, one of Louisa's students who loves astronomy and with whom Dr. Best has much in common
  • Cindy De La Cruz as Jeannie
  • Wattson as Copernicus, an initially unnamed stray dog who repeatedly enters Dr. Best's house against his wishes, causing locals to mistake him as Dr. Best's pet. He is given the name Copernicus by Peter.
  • Martin Clunes as Robert Best, MD, Martin's father and fellow physician. Clunes portrayed Dr. Martin Ellingham in Doc Martin.

Episodes

Production

Development

On May9, 2025, Best Medicine received a straight-to-series order from Fox. The series is wholly owned and produced by Fox Entertainment. Doc Martin was brought to the United States by Propagate Content, alongside All3Media. The American adaptation is written and executive produced by Liz Tuccillo. Propagate's Ben Silverman is an executive producer with Rodney Ferrell, Tuccillo, and Doc Martin executive producers Mark Crowdy and Philippa Braithwaite.

On March 2, 2026, Fox renewed the series for a 12-episode second season.

Casting

The cast is led by Josh Charles as Dr.Martin Best. In July 2025, Abigail Spencer, Josh Segarra, Annie Potts, and Cree joined the main cast. In September 2025, Didi Conn, Clea Lewis, Stephen Spinella, Jason Veasey, John DiMaggio, Carter Shimp, Cindy De La Cruz, and Wattson (a dog) were cast in recurring roles. In October, it was announced that original Doc Martin star Martin Clunes would appear in the role of Martin Best's father.

Filming

On August5, 2025, it was reported that the series began filming in Cornwall, New York.

Broadcast

The series premiered on Fox on January4, 2026.

Reception

The series holds a 77% approval rating on review aggregator Rotten Tomatoes, based on 13 critic reviews. The website's critics consensus reads, "Best Medicine may not refine the medical procedural genre, but it does offer something far more enchanting; compassion, heart and a charming lead that graces all." Metacritic, which uses a weighted average, assigned a score of 56 out of 100 based on five critics, indicating "mixed or average".

References

External links