Bertrix (; ) is a municipality of Wallonia located in the province of Luxembourg, Belgium.
On 1 January 2007 the municipality, which covers 137.7 km<sup>2</sup>, had 8,164 inhabitants, giving a population density of 59.3 inhabitants per km<sup>2</sup>.
Bertrix is home to the NATO reserve Jehonville Air Base.
The municipality consists of the following districts: Auby-sur-Semois, Bertrix, Cugnon, Jehonville, and Orgeo.
Other population centers include:
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Bertrix railway station, in the east of the town, has regular train services to Libramont, Dinant and Virton. On week-days trains run via Virton and Aubange to Arlon.
Bertrix is twinned with: