Barstow is an unincorporated community in Rock Island County, Illinois, United States. As of the 2020 census, Barstow had a population of 89. Barstow is east of East Moline and Silvis. Barstow is located on a wye that connects track owned by the BNSF Railway, including the Barstow Subdivision. These tracks were previously owned by the Chicago, Burlington and Quincy Railroad (CB&Q), and a station once existed within the wye.
Barstow was to be the site of a planned hog plant and a Nascar race track, but both plans were shelved after heavy opposition to them.
Barstow first appeared as a census designated place in the 2020 U.S. census.