Barry M. Trost (born June 13, 1941, in Philadelphia) is an American chemist who is the Job and Gertrud Tamaki Professor Emeritus in the School of Humanities and Sciences at Stanford University. The TsujiâÂÂTrost reaction and the Trost ligand are named after him. He is prominent for advancing the concept of atom economy.
Trost was born in Philadelphia, Pennsylvania on June 13, 1941. He studied at the University of Pennsylvania and obtained his B.A. in 1962. He then attended the Massachusetts Institute of Technology for graduate school, where he worked with Herbert O. House on enolate anions, the Mannich reaction, and the Robinson annulation. Trost graduated with his Ph.D. in 1965.
Trost moved to the University of WisconsinâÂÂMadison to begin his independent career, and was promoted to professor of chemistry in 1969, and the Vilas Research Professor in 1982. In 1987, he moved to Stanford University as professor of chemistry, and was appointed the Job and Gertrud Tamaki Professor of Humanities and Sciences in 1990. He previously served as chair of the department of chemistry.
, Trost has an h-index of 161 according to Google Scholar and of 140 (1040 documents) according to Scopus.
Trost's research focused on chemical synthesis. In order to build complex target molecules from simple molecules, Trost developed new reactions and reagents, and utilized cascade reactions and tandem reactions. Target molecules have potential applications as novel catalysts, as well as antibiotic and anti-tumor therapeutics.