Bamingui-Bangoran is one of the 20 prefectures of the Central African Republic. It covers an area of 58,200 km<sup>2</sup> and had a population of 43,229 as of the 2003 census. The capital is Ndélé. In 2024, official estimates suggest the population reached 85,472 inhabitants.
The Bamingui-Bangoran National Park and Biosphere Reserve is in the prefecture.