Azwile Chamane-Madiba is a South African actress.
In 2016, she played the role of "Zodwa" in Akin Omotoso's film, Vaya, also featuring Phuthi Nakene, Warren Masemola, Nomonde Mbusi, Zimkhitha Nyoka. The film got multiple nominations for the 13th Africa Movie Academy Awards (AMAA) in 2017.