az-Za'ayyem () is a Palestinian village in the Jerusalem Governorate, located 3 kilometers east of Jerusalem in the central West Bank. According to the Palestinian Central Bureau of Statistics, the village had a population of 6,270 in 2017. The healthcare facilities for az-Za'ayyem according to the Ministry of Health are obtained in East Jerusalem.
After the 1967 Six-Day War, az-Za'ayyem has been under Israeli occupation.
After the 1995 accords, 3.8% (or 236 dunams) of the land was classified as Area B, the remaining 96.2% (or 5,896 dunams) as Area C.
Israel has confiscated land from az-Za'ayyem in order to construct two Israeli settlements:
Az-Za'ayyem lies close to Highway 1 to Jerusalem and the az-Za'ayyem check point in the separation barrier.
In December 2025 three residential buildings and eight agricultural buildings were destroyed by Israeli authorities leaving 31 residents homeless.