The athletics events at the 2025 Junior Pan American Games were held at the Athletics Track, located in the Olympic Park in Luque, in the Greater Asuncion area. The events were contested between August 18 and 22, 2025.
45 events were contested, 22 for men, 22 for women, and one mixed. The winner of each event qualified for the 2027 Pan American Games in Lima, Peru.
A total of 496 athletes qualified for the events, based on a Pan American area ranking. Fourteen athletes qualified for each track event except the relay events and the 3000 m steeplechase (12 athletes per race). Twelve qualified for each jumps and throws event. Ten qualified for each combined event (decathlon and heptathlon) and twelve for each race walk event.