Aspergillus megasporus is a species of fungus in the genus Aspergillus. It is from the Aspergillus section. The species was first described in 2017. It has been reported to produce asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulin, emodin, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, preechinulin, physcion, quinolactacin (A1, A2, B), tetracyclic, and tetrahydroauroglaucin.
Aspergillus megasporus has been cultivated on both yeast extract sucrose agar (YES) plates and Malt Extract Agar Oxoidî (MEAOX) plates. The growth morphology of the colonies can be seen in the pictures below.