Argonne is an unincorporated census-designated place in the town of Argonne, Forest County, Wisconsin, United States. Argonne is located at the junction of state highways 32 and 55, north of Crandon. Argonne has a post office with ZIP code 54511. The community was established in 1888. As of the 2020 census, its population was 135, down from 160 at the 2010 census.