Anzat-le-Luguet (; ) is a commune in the Puy-de-Dôme department in Auvergne-Rhône-Alpes in central France. It is in the canton of Brassac-les-Mines.
Anzat-le-Luguet is located in the heart of the volcanic massif of Cézallier, with its highest point situated near the village center: the Signal du Luguet (1,547 m).