Antichan-de-Frontignes (; ) is a commune in the Haute-Garonne department in the Occitanie region of south-western France.
Antichan-de-Frontignes is located at the foot of the Pyrenees in the Comminges region some 40 km east by south-east of Bagnères-de-Bigorre and 19 km south by south-west of Saint-Gaudens. Access to the commune is by the D618 road which branches from the D331 east of Ore and goes to the village then continues north-east by a roundabout route to Juzet-d'Izaut. There is also a local road going from the D618 north of the village to Saint-Pé-d'Ardet. Most of the commune is heavily forested however there is some farmland near the village.
List of Successive Mayors
The inhabitants of the commune are known as Antichanais or Antichanaises in French.