Anthony Creek is a 15 mile-long (24 km) tributary of the Greenbrier River in the southeastern West Virginia, flowing through Greenbrier County before joining the Greenbrier at the town of Anthony. The creek drains a watershed of approximately 34 square miles (90 kmò) and is noted for its excellent trout fishery and recreational paddling opportunities.
According to tradition, the Anthony Creek has the name of John Anthony, a local Indian.