Antanifotsy is a town and commune () in Madagascar. It belongs to the district of Soanierana Ivongo, which is a part of Analanjirofo Region. The population of the commune was estimated to be approximately 15,000 in 2001 commune census.
Only primary schooling is available. The majority 95% of the population of the commune are farmers. The most important crops are rice and cloves, while other important agricultural products are lychee and vanilla. Services provide employment for 3% of the population. Additionally fishing employs 2% of the population.