Anolis macrinii, also known commonly as Macrinius's anole or Macrinius' anole, is a species of lizard in the family Dactyloidae. The species is endemic to Mexico.
The specific name, macrinii, is in honor of Emil Macrinius who was a collector of natural history specimens in Mexico.
Anolis macrinii may attain a snout-to-vent length (SVL) of . The dorsal scales are keeled. The ventral scales are smooth, and are two to three times the size of the dorsal scales.
Anolis macrinii is found in the Mexican state of Oaxaca.
The preferred natural habitat of Anolis macrinii is forest.
Anolis macrinii is arboreal.
Anolis macrinii is oviparous.