The Anderkilla Shahi Jame Mosque (; ) is a Sunni mosque, located in the city of Chittagong, Bangladesh. Built on top of a high hill called Ander-Qila (meaning inner fort), the mosque stands as a monument of the Mughal conquest of Chittagong.
The Persian inscriptions adorning the mosque attest that its construction was undertaken in 1667 CE, during the governorship of Shaista Khan, the Subahdar of Bengal. Contemporary accounts and later traditions hold that the mosque was commissioned under the direction of Buzurg Umed Khan, the eldest son of Shaista Khan and who led the Mughal conquest of Chittagong. However, the inscriptions themselves make no explicit mention of his name.
The mosque was unused for a long time and in the year 1761, the British officials used it to store arms and ammunition. In 1853, the Muslim elites of Chittagong, headed by Hamidullah, approached the British Government and were successful in releasing the mosque for religious purposes in 1855.
In 2025, the Government of Bangladesh decided to initiate the renovation and reconstruction of this 450-year-old mosque.