Amut-piþel II was a king of Qatna in the 18th century BC, during the Middle Bronze IIA.
He was the son of king Ishi-Addu, and his own son and crown prince was named Jaḫad-Abum but it is not known if this heir succeeded due to lack of sources.
His reign is attested in the archive of Mari between c. 1772-1762 BC, after which, Mari was destroyed by Hammurabi of Babylon (r. 1792-1750 BC) and no more information is known about Amut-piþel. Amut-piþel II visited Ugarit and met the king of Mari in year 8 of Zimri-Lim's reign.
He was contemporary with Yarim-Lim of Yamhad (r. 1780-1764 BC), Zimri-Lim of Mari, Hammurabi of Babylon (r. 1792-1750 BC), Ibal-pi-el of Eshnunna (r. 1779-1765 BC), and Rim-Sin I of Larsa (r. 1822-1763 BC).