Alyssa Kleiner (born April 1, 1993) is a retired American soccer player who played as a defender for the Portland Thorns, Washington Spirit, and Seattle Reign in the National Women's Soccer League (NWSL).
Kleiner played for Portland Thorns FC in 2015, appearing in 8 games. In February 2016, she was traded to Washington Spirit in exchange for Katherine Reynolds. In 2016, Kleiner played 17 regular season matches, 12 starts, totaling 1115 minutes She also subbed into the NWSL Championship for an injured Caprice Dydasco. Kleiner scored her first professional goal against Sky Blue FC on July 31. She also had one assist to her name on the season. She was waived by the Spirit before the 2018 season, then signed with Seattle Reign FC on 1 May 2018.