An ñ,ñ-trehalase () is an enzyme with systematic name ñ,ñ-trehalose glucohydrolase. This enzyme catalyzes the chemical reaction
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. It is also called trehalase, and it participates in starch and sucrose metabolism.
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .