Allsbrook is an unincorporated community in Horry County, in the U.S. state of South Carolina.
An early variant name was "Sanford". A rail stop was located in the settlement. A post office called Allsbrook was established in 1915, and remained in operation until 1947. The present name is after N. B. Allsbrook and J. R. Allsbrook, brothers and first settlers.