The Alexander the Great Marathon () is an annual marathon race held in mid-April between Pella (birthplace of Alexander the Great) and Thessaloniki, Greece, since 2006.
It is an AIMS-certified race, and its editions of 2010 and 2011 received IAAF Bronze Label Road Race status.
In addition to the marathon race, the day's events include popular fun runs over five and ten kilometres.
The marathon was first held on .
The 2020 edition of the race was postponed to 2021 due to the coronavirus pandemic, with all entries automatically remaining valid for 2021.
The race starts from Pella, the birthplace of Alexander the Great and capital of Ancient Macedonia, and finishes in Thessaloniki.
Key: Course record (in bold)