Afuze is a town located in the Owan East Local Government Area of Edo State, Nigeria and serves as the administrative headquarters of the Owan East Local Government Area.
The town's name is Afen- su -Uze (meaning the clan of Uze, a type of water cane). Its origins can be traced to be established by Imoigan, one of the descendants of Imah and Uzuanbi. Initially it was a farm camp later, its establishment served as a key trading center along the historic trans-regional trade routes of West Africa. These routes facilitated the exchange of goods such as ivory, spices, and textiles, creating an economy that contributed to Afuze's growth.
Afuze is positioned in the northern part of Edo State. The town's landscape is characterized by a combination of undulating terrain and regional vegetation.