Aetoloacarnania Football Clubs Association () is responsible for football in AetoliaâÂÂAcarnania Prefecture. Its offices are housed in Missolonghi and it is a member of the HFF. It is responsible for running the local league and cup, as well as the youth and children's leagues. It also coordinates the activities of the mixed youth and children's groups, which represent the county at national level. The teams from the former "Kapodistrian" municipalities of Anaktorio, Kekropia and Menidi of Aetoloacarnania do not participate in the Union.
It was founded as an independent Association in 1968, as in previous years the teams of the prefecture of Aetoloacarnania took part in the championships organized by the Achaea Football Clubs Association. The Association was also known as the "Association of Football Clubs of the Prefecture of Aetoloacarnania" (EPSNA). The founding members of the association were AE Messolonghi, Aris Aitoliko, AO Trikardos Katochi, Achilleas Gramatikous, AE Arakynthos Mataranga, AO Pentalofou, AO Pappadata, Iraklis Astakos
The structure of the championship of Aetoloacarnania Football Clubs Association is consisted of 3 divisions
<sup>*</sup>AO Agrinio finished first, but were demoted for attempted bribery and thus the second, Aris Aitoliko were crowned champions.
<sup>**</sup> Due to the suspension of all the championships of the association due to the COVID-19 pandemic, Amvrakikos Loutro were crowned champion and got the ticket to the Gamma Ethniki of the following season. However, the interruption caused the reaction of Panagriniakos, because they were in first place one matchday before the interruption, but they finished second, since Amvrakikos Loutro got a 3âÂÂ0 over AO Chalkia, who had withdrawn from the league, while they were defeated 1âÂÂ0 by Apollon Atsikio. Finally on August 19, while the preparation of the groups of the 2020âÂÂ21 Gamma Ethniki by the HFF was taking place, it was also announced that Panagriniakos would compete in the tournament and thus the prefecture of Aetoloacarnania was represented by 4 clubs.