Adrian Anthony Mayes (born November 17, 1980) is an American former professional football player who was a linebacker in the National Football League (NFL) and Canadian Football League (CFL). He played college football for the LSU Tigers.
Mayes was born in Houston, Texas, where he attended Forest Brook High School.
Mayes played college football as a linebacker and safety at Louisiana State University from 2000 to 2003.
Mayes played in the NFL with the Arizona Cardinals, in NFL Europe with the Berlin Thunder, in the Arena Football League with the Columbus Destroyers and in the CFL with the Toronto Argonauts.