Adriaen de Grijef (1657–1722) was an 18th-century painter from the Dutch Republic.
He was born in Leiden, the son of Jacques de Claeuw. He became a member of the Ghent Guild of St. Luke in 1687, and became a member of the Antwerp guild in 1700. He married in Antwerp and afterward moved to Brussels, where he lived and worked until his death in 1722.