Abura/Asebu/Kwamankese District is one of the twenty-two districts in Central Region, Ghana. Originally created as an ordinary district assembly in 1988, which was created from the former Mfantsiman District Council. The district assembly is located in the southwest part of Central Region and has Essakyir as its capital town.
The ancient Akan Asebu Kingdom was also situated in this District.
As of the 2021 Ghana census, Abura-Asebu-Kwamankese District had a population of 124,465.