AWD 52-39, also known as N,N-diacetoxyethyl-9,10-dihydrolysergamide, is a drug described as a "nootropic" (cognitive enhancer) of the lysergamide family related to lysergic acid diethylamide (LSD) that was never marketed. It was under development by , but development was discontinued. The effects of AWD 52-39 in preclinical studies have been reported. The drug has been found to enhance learning and memory and to produce antidepressant-like effects in rodents. It appears to act upon vascular serotonin receptors. The chemical synthesis and stereochemistry of AWD 52-39 have been described. The drug was first described in the scientific literature by 1989.