AM-919 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid receptor agonist. It is a derivative of HU-210 which has been substituted with a 6ò-(3-hydroxypropyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-919 represents a hybrid structure between the classical dibenzopyran and nonclassical cannabinoid families.
AM-919 is somewhat less potent than HU-210 itself, but is still a potent agonist at both CB<sub>1</sub> and CB<sub>2</sub> with moderate selectivity for CB<sub>1</sub>, with a K<sub>i</sub> of 2.2 nM at CB<sub>1</sub> and 3.4 nM at CB<sub>2</sub>.