ADAMTS13 endopeptidase (, ADAMTS VWF cleaving metalloprotease, ADAMTS-13, ADAMTS13, vWF-cleaving protease, VWF-CP, vWF-degrading protease, Upshaw factor, von Willebrand factor cleaving protease, ADAMTS13 peptidase) is an enzyme. This enzyme catalyses the following chemical reaction
This enzyme belong in the peptidase family M12.