ACS Chemical Neuroscience is a monthly peer-reviewed scientific journal published by the American Chemical Society. It covers research on the molecular underpinnings of nerve function. The journal was established in 2010. The founding editor-in-chief was Craig W. Lindsley (Vanderbilt University), the current editor-in-chief is Jacob Hooker (Harvard Medical School).
According to the journal's website, it has a 2023 impact factor of 4.2.
The journal publishes research letters, articles, and review articles. In addition, specially commissioned articles that describe journal content and advances in neuroscience are solicited.