A-CHMINACA, (ACHMINACA, Adamantyl-CHMINACA, SGT-37), is an indazole-based synthetic cannabinoid that binds to the CB<sub>1</sub> and CB<sub>2</sub> receptors.
It has an EC<sub>50</sub> of 159 nM for human CB<sub>1</sub> receptors.
A-CHMINACA is not hydrolized by human carboxylesterases which increases its half-life.
A-CHMINACA has been sold as a designer drug with one sample having been seized by Polish authorities in Lublin.
It was also detected in samples taken in Toronto in 2020.