In enzymology, a 6-endo-hydroxycineole dehydrogenase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are 6-endo-hydroxycineole and NAD<sup>+</sup>, whereas its 3 products are 6-oxocineole, NADH, and H<sup>+</sup>.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is 6-endo-hydroxycineole:NAD<sup>+</sup> 6-oxidoreductase. This enzyme participates in terpenoid biosynthesis.