6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans. It is a rigid analogue of para-chloroamphetamine (PCA).
According to Nichols et al., 6-CAT is a non-neurotoxic analog of PCA.
Other related compounds that are creditworthy of mention include 6,7-DCAT & 5,6-DCAT [57915-89-6]. These compounds were invented by Bryan Molloy (the inventor of Prozac). These can be thought to be rigid analogs of 3,4-Dichloroamphetamine and might be predicted to be similarly non-neurotoxic. A positional isomer of the aforementioned two compounds is also known to exist in the literature with a 5,8-dichloro substitution pattern (PC9954388). The compound depicted in the latter case is with the spirodecanone pharmacophore.
It is worth pointing out that the precursor used in the synthesis of 6-CAT is called 6-Chloro-2-tetralone [17556-18-2]. This compound is actually the starting material in the synthesis of Bexlosteride.